How to Source Benazepril / Hydrochlorothiazide for Pharmaceutical Formulation

Benazepril / Hydrochlorothiazide (Tablets, 10 mg/12.5 mg, 20 mg/12.5 mg, 20 mg/25 mg) is classified under Heart Disorder. It is therapeutically aligned with reference brands such as Lotensin HCT (USA), Cibadrex (EU/UK). This guide highlights key sourcing factors buyers should consider when procuring high-quality Benazepril / Hydrochlorothiazide for formulation, R&D, or bulk manufacturing.

Product Overview: Benazepril / Hydrochlorothiazide is a combination of an ACE inhibitor (benazepril) and a thiazide diuretic (hydrochlorothiazide) used to manage high blood pressure (hypertension). Benazepril helps relax blood vessels to improve blood flow, while hydrochlorothiazide increases the removal of excess salt and water from the body. This dual action effectively lowers blood pressure and reduces the risk of stroke, heart attack, and kidney problems.

1. Regulatory Compliance & Documentation

Ensure suppliers provide:

• ✔ Valid DMF (Drug Master File)
• ✔ COA (Certificate of Analysis) for each batch
• ✔ GMP, ISO, or ICH Q7 compliance certificates

2. Purity, Grade & Specification Matching

Benazepril / Hydrochlorothiazide must meet exact grade and purity for your dosage form:

• ✔ USP / EP / JP grade verification
• ✔ Particle size distribution check
• ✔ Residual solvent and heavy metal limits

3. Supplier Reliability & Audit History

• ✔ Positive past audit reports
• ✔ Pharma client references
• ✔ Years of proven API manufacturing experience

4. Commercial Terms: Pricing, MOQ & Flexibility

• ✔ Transparent pricing
• ✔ Pilot batch MOQ flexibility
• ✔ Volume-based discounts

5. Lead Time, Inventory & Logistics

Typical lead time for Benazepril / Hydrochlorothiazide is 4–6 weeks.

• ✔ Emergency dispatch options
• ✔ Regional warehousing
• ✔ Special storage if needed

6. Formulation Support

• ✔ Technical datasheets
• ✔ Sample availability
• ✔ Stability study support

Conclusion

Sourcing Benazepril / Hydrochlorothiazide is more than procurement—it’s a strategic partnership. With its tablets form and 10 mg/12.5 mg, 20 mg/12.5 mg, 20 mg/25 mg specification, choosing a compliant supplier ensures consistent quality and regulatory approval. Prioritize documentation, verify compatibility, and build relationships with transparent, reliable suppliers to secure long-term success.

Frequently Asked Questions For Sourcing of Benazepril / Hydrochlorothiazide