How to Source Tramadol + Paracetamol tablets for Pharmaceutical Formulation

Tramadol + Paracetamol tablets (Oral Tablets, 37.5 mg tramadol + 325 mg paracetamol; 75 mg + 650 mg) is classified under Analgesic. It is therapeutically aligned with reference brands such as Ultracet(US); Tramacet(EU). This guide highlights key sourcing factors buyers should consider when procuring high-quality Tramadol + Paracetamol tablets for formulation, R&D, or bulk manufacturing.

Product Overview: Tramadol + Paracetamol tablets combine tramadol’s action as a weak opioid agonist and serotonin reuptake inhibitor with paracetamol’s inhibition of prostaglandin synthesis. This dual mechanism provides effective relief from moderate to severe pain, offering rapid onset, improved analgesia, and reduced opioid dose when used responsibly under medical supervision.

1. Regulatory Compliance & Documentation

Ensure suppliers provide:

• ✔ Valid DMF (Drug Master File)
• ✔ COA (Certificate of Analysis) for each batch
• ✔ GMP, ISO, or ICH Q7 compliance certificates

2. Purity, Grade & Specification Matching

Tramadol + Paracetamol tablets must meet exact grade and purity for your dosage form:

• ✔ USP / EP / JP grade verification
• ✔ Particle size distribution check
• ✔ Residual solvent and heavy metal limits

3. Supplier Reliability & Audit History

• ✔ Positive past audit reports
• ✔ Pharma client references
• ✔ Years of proven API manufacturing experience

4. Commercial Terms: Pricing, MOQ & Flexibility

• ✔ Transparent pricing
• ✔ Pilot batch MOQ flexibility
• ✔ Volume-based discounts

5. Lead Time, Inventory & Logistics

Typical lead time for Tramadol + Paracetamol tablets is 4–6 weeks.

• ✔ Emergency dispatch options
• ✔ Regional warehousing
• ✔ Special storage if needed

6. Formulation Support

• ✔ Technical datasheets
• ✔ Sample availability
• ✔ Stability study support

Conclusion

Sourcing Tramadol + Paracetamol tablets is more than procurement—it’s a strategic partnership. With its oral tablets form and 37.5 mg tramadol + 325 mg paracetamol; 75 mg + 650 mg specification, choosing a compliant supplier ensures consistent quality and regulatory approval. Prioritize documentation, verify compatibility, and build relationships with transparent, reliable suppliers to secure long-term success.

Frequently Asked Questions For Sourcing of Tramadol + Paracetamol tablets