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Methylnaltrexone Bromide bulk supplier for pharma manufacturers

Methylnaltrexone Bromide Suppliers & Bulk Manufacturers

Available Forms: Tablet / Injection

Available Strengths: 12 mg/mL , 8 mg/mL , 450 mg

Reference Brands: Relistor (USA)

Category: Gastrointestinal Drugs

Methylnaltrexone Bromide is available in Tablet / Injection and strengths such as 12 mg/mL , 8 mg/mL , 450 mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Methylnaltrexone Bromide is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Methylnaltrexone Bromide can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

Methylnaltrexone bromide is a peripherally acting mu-opioid receptor antagonist used to relieve constipation caused by opioid medications, commonly referred to as opioid-induced constipation (OIC). It is marketed under the brand name Relistor and is indicated for adult patients experiencing constipation due to opioid use for chronic pain, including pain associated with cancer, cancer treatment, or other advanced illnesses.

This medication works by selectively binding to opioid receptors in the gastrointestinal tract without crossing the blood-brain barrier, which allows it to block the constipating effects of opioids while preserving their pain-relieving properties. Methylnaltrexone bromide can be administered subcutaneously for rapid relief or orally for chronic management, depending on the patient’s condition and treatment plan.

By targeting peripheral opioid receptors, methylnaltrexone bromide effectively restores bowel function and provides relief from constipation without compromising analgesia. Its mechanism and safety profile make it a valuable option for patients who require long-term opioid therapy and need to maintain gastrointestinal regularity under medical supervision.

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Frequently Asked Questions

Methylnaltrexone bromide is used to treat opioid-induced constipation in patients with chronic non-cancer pain or advanced illness receiving palliative care, without affecting opioid pain relief.

Methylnaltrexone bromide is a synthetically manufactured quaternary ammonium derivative of naltrexone, designed to act selectively on peripheral mu-opioid receptors in the gastrointestinal tract.

The trade name of methylnaltrexone bromide is Relistor.

Relistor is developed and marketed by Bausch Health Companies Inc. (previously Valeant Pharmaceuticals).

The generic name of Methylnaltrexone Bromide is methylnaltrexone bromide.

The brand name of Methylnaltrexone Bromide is Relistor.

Methylnaltrexone bromide injection and tablets are manufactured in GMP-compliant pharmaceutical facilities in the USA and EU, depending on market distribution.

Yes, Methylnaltrexone Bromide is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Methylnaltrexone Bromide is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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