Naftifine Hydrochloride Suppliers & Bulk Manufacturers
Available Forms: Cream / Gel
Available Strengths: 1 %, 2%
Reference Brands: Naftin (USA), Xolafin (USA)
Category: Anti-fungal
Naftifine Hydrochloride is available in Cream / Gel and strengths such as 1 %, 2%. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Naftifine Hydrochloride is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.
| Technical Specifications & Supply Details | |
|---|---|
| Lead Time | 7 to 60 days (depending on batch size & schedule) |
| MOQ | As per manufacturer’s batch size |
| COA | Available with every batch |
| Regulatory Dossier / DMF | Available upon request |
| Export Documentation | FSC, COA, Manufacturing License, Product Permission |
| Standards | IP, BP, USP |
| Certifications | WHO-GMP, EU-GMP, USFDA (as applicable) |
Naftifine Hydrochloride can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.
Product Description:
Naftifine is a topical antifungal agent known for its triple action, providing antifungal, antibacterial, and anti-inflammatory effects. Its antifungal activity is primarily based on the inhibition of the squalene-2,3-epoxidase enzyme, a key enzyme involved in the biosynthesis of ergosterol. Ergosterol is an essential component of fungal cell membranes, and inhibition of its production leads to disruption of normal fungal cell membrane formation.
In certain fungal species, naftifine also exhibits fungicidal activity due to the accumulation of squalenes within the fungal cells. This buildup causes structural damage to the fungal cell membranes, including the endoplasmic reticulum, ultimately leading to fungal cell death. Naftifine demonstrates predominantly fungicidal activity against dermatophytes and molds, while showing mainly fungistatic activity against yeasts.
In addition to its antifungal properties, naftifine has proven antibacterial activity, making it effective in the treatment of bacterial skin infections such as pyoderma. Its combined antifungal, antibacterial, and anti-inflammatory actions make naftifine a valuable option for managing mixed or complicated skin infections.
The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Naftifine is used to treat fungal skin infections such as athlete’s foot (tinea pedis), jock itch (tinea cruris), and ringworm (tinea corporis).
Naftifine is a synthetically manufactured antifungal agent produced through chemical synthesis.
Naftifine is sold under trade names such as Naftin and Xolafin, depending on the market.
Naftin was originally marketed by Merz Pharmaceuticals. Generic versions are manufactured by multiple pharmaceutical companies worldwide.
The generic name of Naftifine is naftifine hydrochloride.
Brand names of Naftifine include Naftin and Xolafin, along with generic equivalents.
Naftifine is manufactured in several countries including the United States, India, and European nations, depending on the manufacturer and regulatory approvals.
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