Pioglitazone Hydrochloride Suppliers & Bulk Manufacturers
Available Forms: Tablets
Available Strengths: 15 mg, 30 mg, 45 mg
Reference Brands: Actos (USA)
Category: Diabetes
Pioglitazone Hydrochloride is available in Tablets and strengths such as 15 mg, 30 mg, 45 mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Pioglitazone Hydrochloride is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.
| Technical Specifications & Supply Details | |
|---|---|
| Lead Time | 7 to 60 days (depending on batch size & schedule) |
| MOQ | As per manufacturer’s batch size |
| COA | Available with every batch |
| Regulatory Dossier / DMF | Available upon request |
| Export Documentation | FSC, COA, Manufacturing License, Product Permission |
| Standards | IP, BP, USP |
| Certifications | WHO-GMP, EU-GMP, USFDA (as applicable) |
Pioglitazone Hydrochloride can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.
Product Description:
Pioglitazone Hydrochloride is the hydrochloride salt of an orally active thiazolidinedione with antidiabetic properties and potential antineoplastic activity. It belongs to the TZD class and acts primarily by activating peroxisome proliferator-activated receptor gamma (PPAR-γ), a ligand-activated transcription factor that regulates the expression of genes involved in glucose and lipid metabolism. Activation of PPAR-γ improves insulin sensitivity in peripheral tissues and the liver, enhances adipocyte differentiation, and modulates the transcription of insulin-responsive genes, helping to lower blood glucose levels in patients with type 2 diabetes mellitus. Pioglitazone also exhibits additional cellular effects, including inhibition of macrophage and monocyte activation, induction of cell differentiation, and suppression of cell growth and angiogenesis, which may contribute to its potential antineoplastic properties. The medication is administered orally in tablet form and can be used alone or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin, along with diet and exercise. Sold under brand names such as Actos®, Glustin®, and other regional brands, pioglitazone hydrochloride provides a versatile option for improving glycemic control and potentially modulating other metabolic and cellular pathways.
The Trade Mark owner has been correctly identified under the heading Manufacturer / TM Owner as required by the Act.
Frequently Asked Questions
Pioglitazone Hydrochloride is used as an oral antidiabetic medication to improve glycemic control in adults with type 2 diabetes mellitus, either alone or in combination with other antidiabetic agents such as metformin, sulfonylureas, or insulin. It is taken together with diet and exercise to help lower blood glucose levels.
Pioglitazone Hydrochloride is the hydrochloride salt of pioglitazone, a thiazolidinedione (TZD) class compound that activates peroxisome proliferator‑activated receptor gamma (PPAR‑γ) to enhance insulin sensitivity in peripheral tissues and liver.
Common trade names for Pioglitazone Hydrochloride include Actos®, and in some regions products are marketed as Glustin®, Glizone®, or Pioz® among others.
Pioglitazone Hydrochloride is manufactured by multiple pharmaceutical companies globally, including the originator Takeda Pharmaceuticals for Actos® and various generic manufacturers.
The generic name is Pioglitazone Hydrochloride.
Brand names include Actos®, Glustin®, Glizone®, Pioz®, and other regional brands depending on the manufacturer and market.
Pioglitazone Hydrochloride is manufactured in various countries including the USA, EU, India, and other regions by different pharmaceutical companies that produce both branded and generic versions.
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