Sugammadex Sodium Suppliers & Bulk Manufacturers
Available Forms: Injection
Available Strengths: 100 mg/mL
Reference Brands: Bridion (USA)
Category:
Anaesthetics
Sugammadex Sodium is available in Injection
and strengths such as 100 mg/mL.
Sourced from GMP-certified and ISO-compliant manufacturers, this API meets
global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical
formulation and commercial manufacturing, Sugammadex Sodium is supplied in
bulk quantities with complete regulatory support including DMF, COA, and MSDS.
|
Technical Specifications & Supply Details
|
| Lead Time |
7 to 60 days (depending on batch size & schedule) |
| MOQ |
As per manufacturer’s batch size |
| COA |
Available with every batch |
| Regulatory Dossier / DMF |
Available upon request |
| Export Documentation |
FSC, COA, Manufacturing License, Product Permission |
| Standards |
IP, BP, USP |
| Certifications |
WHO-GMP, EU-GMP, USFDA (as applicable) |
Sugammadex Sodium can be exported to over 30 countries across Asia, Africa, Europe,
and Latin America. Flexible packaging, competitive pricing, and a verified supplier
network make Pharmatradz a trusted sourcing partner for pharmaceutical companies
and contract manufacturers worldwide.
Product Description:
Sugammadex sodium is the sodium salt form of sugammadex, a biologically inert and highly selective relaxant binding agent (SRBA) used for the rapid reversal of neuromuscular blockade induced by steroidal non-depolarizing neuromuscular blocking drugs. Structurally, it is a modified anionic gamma-cyclodextrin derivative with a hydrophilic outer surface and a lipophilic central cavity, specifically designed to encapsulate target molecules.
After intravenous administration, sugammadex selectively and reversibly binds to aminosteroid neuromuscular blocking agents such as rocuronium and vecuronium. Its negatively charged carboxyl-thio-ether side chains interact with the positively charged quaternary nitrogen of these agents, forming a tight inclusion complex. This encapsulation reduces the free concentration of the neuromuscular blocker in plasma, creating a concentration gradient that draws the drug away from nicotinic acetylcholine receptors at the neuromuscular junction. As a result, normal neuromuscular transmission is rapidly restored without relying on acetylcholinesterase inhibition.
Sugammadex sodium is widely used in anesthesia practice due to its rapid onset, predictable reversal, and favorable safety profile. It enables faster recovery of muscle function, improves operating room efficiency, and reduces complications associated with residual neuromuscular blockade, making it a valuable agent in modern perioperative care.
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