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Alprazolam / Sertraline Tablet bulk supplier for pharma manufacturers

Alprazolam / Sertraline Tablet Suppliers & Bulk Manufacturers

Available Forms: Tablets

Available Strengths: 0.25mg + 25mg

Reference Brands: Various Indian Brand Available

Category: Antipsychotropic Drugs

Alprazolam + Sertraline is a combination of two medicines: Alprazolam and Sertraline, which has anxiety-lowering and mood-enhancing effects. Alprazolam is a benzodiazepine (BZD) which increases the action of GABA, a chemical messenger that suppresses the abnormal activity of the nerve cells in the brain. Sertraline is selective serotonin reuptake inhibitor (SSRI) which increases the levels of serotonin, a chemical messenger that improves mood. Alprazolam / Sertraline Tablet is available in Tablets and strengths such as 0.25mg + 25mg. Sourced from GMP-certified and ISO-compliant manufacturers, this API meets global pharmacopeia standards (USP/EP/JP as applicable). Ideal for pharmaceutical formulation and commercial manufacturing, Alprazolam / Sertraline Tablet is supplied in bulk quantities with complete regulatory support including DMF, COA, and MSDS.

Technical Specifications & Supply Details
Lead Time 7 to 60 days (depending on batch size & schedule)
MOQ As per manufacturer’s batch size
COA Available with every batch
Regulatory Dossier / DMF Available upon request
Export Documentation FSC, COA, Manufacturing License, Product Permission
Standards IP, BP, USP
Certifications WHO-GMP, EU-GMP, USFDA (as applicable)

Alprazolam / Sertraline Tablet can be exported to over 30 countries across Asia, Africa, Europe, and Latin America. Flexible packaging, competitive pricing, and a verified supplier network make Pharmatradz a trusted sourcing partner for pharmaceutical companies and contract manufacturers worldwide.

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📘 Sourcing Guide

Product Description:

A 12-week, placebo-controlled outpatient study was conducted to evaluate the efficacy and safety of sertraline hydrochloride and alprazolam in patients diagnosed with panic disorder, with and without agoraphobia, according to ICD-10 criteria. The study included 40 adult patients aged 18 years and above, who were randomly assigned to receive either sertraline or alprazolam in fixed doses.

Sertraline was administered at a dose of 20 mg per day, while alprazolam was given in doses ranging from 1 to 1.5 mg per day. The evaluation focused on key clinical parameters, including the frequency of panic attacks, severity of agoraphobia, and levels of anticipatory anxiety.

The results demonstrated that both sertraline and alprazolam significantly reduced the frequency of panic attacks in patients with panic disorder. In addition, notable improvements were observed in symptoms of agoraphobia and anticipatory anxiety. These findings highlight the effectiveness of both medications in managing panic disorder, with each offering therapeutic benefits in reducing acute anxiety symptoms and improving overall patient outcomes when used under appropriate medical supervision.

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Frequently Asked Questions

This combination is used for the treatment of anxiety disorders associated with depression, panic disorders, and mixed anxiety-depressive conditions. It helps provide rapid relief from anxiety symptoms while also addressing underlying depression.

It is made from alprazolam, a benzodiazepine that enhances GABA activity to produce a calming effect, and sertraline hydrochloride, an SSRI that increases serotonin levels in the brain to improve mood and emotional balance.

Common trade names include Alprasafe Plus, Restyl Plus, Serlift Plus, Alprazolam + Sertraline Tablets (generic labeling), and other region-specific branded generics.

This combination is manufactured by multiple pharmaceutical companies, especially in India and emerging markets, including companies like Sun Pharma, Cipla, Intas, and others.

The generic names are alprazolam and sertraline hydrochloride.

Brand names include Alprasafe Plus, Restyl Plus, Serlift Plus, and other local branded generics.

It is primarily manufactured in India and supplied to various regions including Asia, Africa, and LATAM markets, with limited availability in regulated markets like the USA and EU as a fixed-dose combination.

Yes, Alprazolam / Sertraline Tablet is available with DMF and other regulatory documents such as COA and MSDS. These can be provided upon request for qualified buyers.

Absolutely. Sample requests are accepted for formulation trials and quality checks. Please submit an enquiry to initiate the process.

Our manufacturing partners are GMP-certified and comply with ISO and WHO standards, ensuring global quality benchmarks.

Lead times vary based on quantity and destination, but most orders are fulfilled within 1–3 weeks. Express shipping options are available.

Yes, Alprazolam / Sertraline Tablet is exported to over 30 countries across Asia, Africa, Europe, and Latin America. We support documentation for customs and regulatory clearance.

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